Reconstructing transcription factor activities in hierarchical transcription network motifs
نویسندگان
چکیده
منابع مشابه
Reconstructing transcription factor activities in hierarchical transcription network motifs
MOTIVATION A knowledge of the dynamics of transcription factors is fundamental to understand the transcriptional regulation mechanism. Nowadays, an experimental measure of transcription factor activities in vivo represents a challenge. Several methods have been developed to infer these activities from easily measurable quantities such as mRNA expression of target genes. A limitation of these me...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2011
ISSN: 1460-2059,1367-4803
DOI: 10.1093/bioinformatics/btr487